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pH and Acidosis
Michael Lam, M.D., M.P.H., A.B.A.A.M.* According to the research of Dr Enderlein, our bodies can only be healed of any
chronic illness when our blood is at a normal, slightly alkaline pH. What exactly does pH mean? pH is the short form for potential hydrogen.
The pH of any solution is the measure of its hydrogen-ion concentration.
The higher the pH reading, the more alkaline and oxygen rich the fluid is.
The lower the pH reading, the more acidic and oxygen deprived the fluid is.
The pH ranges from 0 to 14, with 7.0 being neutral. Indicator above 7.0 is alkaline
and below 7.0 is considered acidic. A normal healthy body will have an almost equal blood pH of acidity and
alkalinity. The most ideal pH balance is 7.4,
which means that it is slightly
more alkaline than acid. Only when the pH level is balance that our bodies can
then effectively assimilate vitamins, minerals and food supplements. As such,
our body pH's determines everything. An acid pH body is more prone to illness.In an acidic environment, red blood
cells cannot repel and stick together like a stack of coins, forming what is called
rouleau formation. This formation limits the amount of oxygen carrying capacity
because red blood cells sandwiched between the two ends are compressed against each
other and therefore unable to carry oxygen. Reduced oxygen leads fatigue, lack of
energy, and weakness, just to mention a few symptoms. Furthermore, cancer cells
strives in an oxygen deprived environment (anaerobic) much better than in an oxygen
rich environment. The importance of maintaining optimum pH is therefore a critical factor in
balancing proper internal terrain to deter cancer, infection, and a host of
inflammatory disease. The majority of these conditions worsen in an acidic environment.
They do not do well in an acidic environment. The normal human cell is slightly alkaline and has an abundance of molecular oxygen.
The cancer cell is acidic and cannot survive in an oxygen rich environment. As such,
we can conclude that pH balance is very important to one's health, especially for
the cancer patient. The pH indicators are an exponent number of 10. A small difference in pH will
translate to a big difference in the number of oxygen or OH-ions. A difference of 1
in a pH value means ten times the difference in the number of OH-ions.
A difference of 2 means one hundred times the difference in the number of OH-ions.
In other words, a blood with a pH value of 7.45 contains 64.9% more oxygen than blood
with a pH value of 7.30. Acidosis is a pH imbalance where the body has accumulated too much acid and does
not have sufficient acid neutralizer to neutralize the effects. Acidosis may result
from a lack of insulin, a starvation diet or even a gastrointestinal disorder like
vomiting and diarrhea. The acidic biochemical type is not meant to represent the absolute pH measurement
of the blood system, which generally requires a laboratory test performed in hospitals
known as blood gases. While certain areas of the body normally may have an more acidic
environment (stomach, kidneys, bladder) than others, the overall pH of the body and
blood normally must be maintained within a narrow range of alkalinity (pH 7.30 - 7.45.
An absolute blood measurement of acidity (pH below 7.0) is incompatible with life. 1.) The metabolism and/or incomplete breakdown (oxidation) of foodstuffs or metabolic
"waste" produced as a by-product of cellular activity. During normal cellular
respiration and energy production, acids as produced as part or "waste" products.
These acid must be "balanced", neutralized, or removed by the body's buffering and
detoxification systems through the kidneys, lungs, liver, and blood. 2.) The consumption of acid present in the food, air, and water supply. Nitrogen
emissions from automobiles and industrial plants, food dyes, sprays, waxes, preservatives,
additives, artificial sweeteners, fertilizers, water pollutants, and even chloride
and fluoride in tap water are just some of the highly acidic chemicals are ingested by
millions everyday. Acidosis leads to serious problems with major organs such as the liver, heart or
kidneys. In this article, we will be looking into some of the reasons as to why we
should avoid acidosis. 1.) It corrodes arteries, veins, and heart tissues. Like acid eating into marble, acidosis erodes and eats into cell wall membranes of
the heart, arteries and veins. During this process of erosion, our heart structures
and inter connective tissues are weakened. All living tissues are sensitive to their chemical environment. The muscle cells
of the heart are no different. The entire cardiovascular system is directly affected
by blood plasma pH and works as one large working "system of tubular muscles" to carry
blood and nutrients to all living tissue in the body. The pumping of the heart drives
blood through the arteries, veins and capillary beds and helps to regulate blood
pressure and the flow of blood circulation. The heart is normal when the pH of blood plasma is slightly alkaline, having a
pH of 7.35 to 7.41. When the heart plasma lowers to an acidic pH of less than 7.35
it gradually erodes away the smooth muscle tissues of the inner walls of the arteries
and veins, as well as the heart itself. This process will start to weaken the
structural composition of the heart, arterial and venous walls, causing lesions
and microscopic tearing throughout its framework. At the same time, an acid
pH destabilizes free ionic balances within circulation, increasing the populations
of positively charges particles (cations, an ion with a positive charge of
electricity: H , Ca ) which directly interfere with the muscle contractility
(contraction and relaxation) of the heart and arteries. Acid pH changes of blood are now thought to result in the following: The structural weakening of the cardiocascularity also creates irregularities of
blood pressure, which further exacerbates the above problems. 2.) It accelerates free-radical damage and premature aging. Acidosis leads to partial lipid breakdown and destructive oxidative cascades
accelerating free radical damage of cell walls and intracellular membrane structures.
In this process, many healthy cells are destroyed. Acidosis is the first step towards premature aging and accelerated oxidative
cascades of cell wall destruction. Signs of acidosis may include wrinkling, age spots,
failing hormonal systems, interfering with eyesight, memory, and a host of other
age-related phenomena. Unwanted wastes not properly eliminated from the body actually
poison the cells. 3.) It disrupts lipid and fatty acid metabolism. Acidosis generally disrupts lipid and fatty acid, which are involved in nerve and
brain function. This disruption causes neurological problems such as MS, MD as well as
problems with hormonal balance within the endocrine system. An acidic environment also causes LDL-cholesterol to be laid down at an accelerated
rate in the heart, inappropriately lining and clogging up the vascular network.
In other words, an acid pH initiates electrostatic potential, damaging arterial walls,
which in turn initiates a PDGF-dependent immune response, causing cholesterol
oxidation and the formation of plaque with heavy metals. 4.) It leads to weight gain and diabetes. It is very likely that an acid pH, from an imbalanced diet, produces a condition,
which stimulates the predetermined genetic response to starvation and famine.
Thereafter, the body will have to increasingly hoard every calorie consumed and
store it as fat. Some people reckon that an acidic pH immediately signals the powerful genetic
response to an impending famine, directly interpreting with the all important
and very sensitive Insulin-Glucagon Axis. When this happens, it makes the body
produce more insulin than usual, and in turn, produce more fats and store it. On the other hand, a healthy and slightly alkaline pH will yield normal fat
burning metabolic activities, making no demands on the body to produce extra
insulin and make fats. As such, this allows fat to be burned and naturally lost.
A healthy pH diet is also less likely to have any yo-yo effects, or rebounding
from a diet with additional weight gain. We should try to maintain a healthy s
lightly alkaline pH so as to allow fats to be burnt normally for energy,
rather than hoarded and stored under the mistaken biochemical belief of an
impending famine. Acidosis also disrupts the insulin producing pancreatic beta cells. These beta
cells are especially sensitive to pH and cannot survive if the body is too acidic.
When this occurs, beta cells will lose phase with one another. Their cellular
communication will be thwarted and the body's immune system will start to over-respond.
Stress within the cells will increase, making them more difficult to perform adequately
and survive. 5.) It alters the energy metabolism and reserve. When your body has an acidic pH, it will prevent efficient cellular and body
metabolism. Acidosis results in chemical ionic disturbances, interfering with
cellular communications and functions. Acidosis reduces plus calcium binding of
plasma proteins, therefore reducing the effectiveness of this intracellular signal.
It also results in a disease of calcium cations (positive calcium) entry through
positive calcium channels. This leads to a reduction of cardiac contractibility,
or the ability of the heart to pump efficiently and rhythmically. Positive calcium and hydrogen regulate the activities of intracellular proteins
and are driven out of the cells by the "Sodium-Potassium pump" (Na-K pump). This pump
provides a strong incentive for sodium to be driven into cells. It also regulates the
amount of both sodium and potassium in the body stores, and uses as much as 25 percent
of our caloric input daily. Positive calcium exchanges the plus sodium, being forced
out of cells, but naturally, the electrochemical gradient for positive calcium favors
both positive hydrogen and positive calcium entry into cells, as there is less calcium
and positive hydrogen in cells than in the extra-cellular fluids. In extra-cellular
fluids, there is 10 times more the amount of positive sodium. In acidic solutions, less plus sodium is available, therefore slowing down the
processing and induction of nutritional items going into the cells. This increases
positive hydrogen and calcium buildup within the plasma, making it more available
to electro-statically bind with LDL-Cholesterol. As a result, with free positive
calcium populations and channels being disrupted, calcium may become inordinately
leached from the bone masses. This causes osteoporosis. In a nutshell, an acidic
pH drains us of energy and disallows stored energy reserves to be used. 6.) It slow the delivery of oxygen into the cell. Acidosis reduces oxygen in the blood. As all living tissues, especially
the heart and brain need oxygen to function; a lack of it will lead to eventual
death. Having an acidic pH will reduce the amount of oxygen that is delivered
to the cells. They will eventually die. It is important to note that the body's biochemistry is an important but just
one of many tools to help the physician understand the whole body. pH in an of
itself is not a diagnostic tool and is not a medical diagnosis as a disease entity. What then happens when the body is too acidic? An acidic balance will: Most of the time, the body becomes acidic due to a diet rich in acids,
emotional stress, toxic overload, and/or immune reactions or any process
that deprives the cells of oxygen and other nutrients. When this happens,
the body will try to compensate for acidic pH by using alkaline minerals such as
calcium. As a result, calcium is removed from the bones, causing osteoporosis. Acidosis, which is an extended time in the acid pH state, can result in
rheumatoid arthritis, diabetes, lupus, tuberculosis, osteoporosis, high blood
pressure and most cancers. Two main factors leading to cancer are an acidic pH and a lack of oxygen.
As such, are we able to manipulate these two factors so as to prevent and
control cancer? Everyone knows that cancer needs an acidic and low oxygen environment to
survive and flourish. Research has proven that terminal cancer patients have an
acidity level of 1,000 times more than normal healthy people. The vast majority
of terminal cancer patients have a very acidic pH. Why is this so? The reason is simple. Without oxygen, glucose undergoing fermentation becomes
lactic acid. This causes the pH of the cell to drop to 7.0. In more advance cancer
cases, the pH level falls further to 6.5. Sometimes, the level can even fall to
6.0 and 5.7 or lower. The basic truth is that our bodies simply cannot fight
diseases if our pH is not properly balanced. The body undergoes an natural and ongoing balancing act constantly.
Underlying regulatory forces work continually to balance an acidic
body chemistry to remove excess acid and return the body to a more neutral state. These internal buffering mechanisms include: Many minerals and other factors involved in maintaining a normal body chemistry
fluctuate throughout the day in response to variations in serum and electrolyte
concentrations, as well as dietary influences. Such minerals acts as a buffer and a
balancer to maintain the body in a balanced chemistry state in order for proper enzyme
activations to occur. Long term acidosis can lead to mineral depletion and osteoporosis.
Calcium, for example, has been shown to enter the intracellular compartment in an
effort to maintain ionic balance when magnesium is deficient, resulting in
calcification of the cell and resulting hypertension. High dose of calcium
supplementation has been shown to reduce hypertension. These levels, resulting from the breakdown of meat byproducts (purines),
contribute to the development of an acidotic condition. Excessive protein intake,
including meats, viscera, leguminous vegetables increases uric acid production.
Other causes of hyperuricemia include gout, renal failure, lactic acid buildup
(alcohol abuse, extreme exercise and pregnancy, malignant neoplasms, and the use of
diuretics. These levels, resulting from the breakdown of endogenous fat or excessive
ingestion of sugar (including grains). Diets excessive in complex carbohydrates
(such as pasta, breads and starches) is the most common cause of elevated triglyceride
levels. Only 20% of the ingested sugar load can be burned or stored as glycogen at any
one meal. The remainder 80% will be converted to triglyceride which can contribute
to the buildup of acidity, or stored as fat deposits. Although saliva is generally more acidic than blood, it is a fairly good indicator
of health. It tells you what your body retains. Salivary pH is a fair indicator of
health for extracellular fluids and their alkaline mineral reserves. The optimal pH for saliva is between 6.4 to 6.8. A reading lower than 6.4 means
that there is not enough alkaline reserves. After meals, the saliva pH should rise
to 7.8 or higher. If there is no increase, it will imply that the body has a deficiency
in alkaline minerals especially calcium and magnesium. Food will not be absorbed and
assimilated well. To deviate from an ideal salivary pH for an extended time will lead
to illnesses. If the salivary pH level remains too low, we should take more fruits, vegetables
and mineral water and avoid strong acidifiers such as sodas, whole wheat and red meat
to maintain its balance. The pH of the urine is an indication as to how well the body is working to
maintain a proper pH of the blood. It reflects the efforts of the body via the
kidneys, adrenals, lungs and gonads through the buffer salts and hormones. The
urine also shows the alkaline building (anabolic) and acid tearing down (catabolic)
cycles. By taking urine samples, we can have assess to a fairly accurate picture
of our body chemistry as our kidneys filter out the buffer salts of pH regulation
and provide values based on what the body is eliminating. The urine pH can vary
from around 4.5 to 9.0, but the ideal range is still 5.8 to 6.8. To increase the alkalinity in our blood, we can consume these foods: almonds,
aloe vera, apples, apricots, bee pollen, buckwheat, cabbage, cantaloupe, celery,
carrots, cucumbers, dairy products except hard cheese, dates, pulse, poached eggs,
figs, grapefruit, honey, lettuce, millet, parsley, raisins, peaches, fresh red potatoes,
pineapple, soy products, sprouted seeds, cooked spinach, turnip tops, wakame miso
soup, azuki beans, rice and mineral water. In conclusion, balancing your pH is a major step towards optimal well-being and
better health. Acidosis is the main cause of calcium deficiency disease. After many
studies, scientists can safely conclude that healthy people have body fluids that
are alkaline (high pH) whereas sick people have body fluids that are acidic (low pH). The blood is normally maintained in an alkaline state. An acidic state reduces
blood oxygen carrying capacity and promotes a higher valance state of polymorphism. Foods are generally broken down and converted into either acidic or alkaline
substrates with digestion. A person with an acid metabolic condition should
emphasize the consumption of alkaline forming foods in the diet, with 60-70%
alkaline forming foods, and 30-40% acid forming food by volume. Do not simply eat all alkaline forming food, as some acid formation is necessary
to generate metabolic activity and maintain homeostasis. Too alkaline a body can
predispose the body to certain types of infection. Here are some of the common acid and alkaline forming foods. These categories
are based on the body's reaction to a moderate amount of each. Excess amounts may
produce the opposite effect. Message from Dr. Lam I hope you have enjoyed reading this article. If you have areas you don't
understand, comments (good or bad), or if you have a specific health concern,
feel free to write to me by clicking here. *About The Author Michael Lam, M.D., M.P.H., A.B.A.A.M. is a specialist in Preventive and
Anti-Aging Medicine. He is currently the Director of Medical Education at the
Academy of Anti-Aging Research, U.S.A. He received his Bachelor of Science
degree from Oregon State University, and his Doctor of Medicine degree from
Loma Linda University School of Medicine, California. He also holds a Masters of
Public Health degree and is Board Certification in Anti-aging Medicine by
the American Board of Anti-Aging Medicine. Dr. Lam pioneered the formulation of
the three clinical phases of aging as well as the concept of diagnosis and
treatment of sub-clinical age related degenerative diseases to deter the
aging process. Dr. Lam has been published extensively in this field.
He is the author of The Five Proven Secrets to Longevity (available on-line).
He also serves as editor of the Journal of Anti-Aging Research. The above article was written by Dr. Lam. If you have a specific health concern and wish Dr. Lam's personalized
nutritional recommendation, write to Dr. Lam by clicking
here. Please note: No relationship whatsoever exists between Dr. Lam and
the owner of this website.
Dr. Lam's article is posted here for informational purposes only. Information presented here is for general educational purposes only. |